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Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration.

Shanshan LuoChuiyu KongShuang ZhaoXin TangYu WangXuechun ZhouRui LiXingeng LiuXinlong TangShixiu SunWei XieZhi-Ren ZhangQing JingAihua GuFeng ChenDongjin WangHong WangYi HanLi-Ping XieYong Ji
Published in: Circulation (2023)
, impairs PDI S-sulfhydration, and drives AAD. The regulation of this pathway effectively prevents AAD progression.
Keyphrases
  • aortic aneurysm
  • epithelial mesenchymal transition
  • endothelial cells
  • long non coding rna
  • protein protein
  • amino acid
  • binding protein
  • histone deacetylase
  • small molecule