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CHK1 monitors spindle assembly checkpoint and DNA damage repair during the first cleavage of mouse early embryos.

Jia-Qian JuXiao-Han LiMeng-Hao PanYao XuMing-Hong SunYi XuShao-Chen Sun
Published in: Cell proliferation (2020)
Our results indicate that CHK1 is a key regulator of the SAC and DNA damage repair during early embryonic development in mice.
Keyphrases
  • dna damage
  • dna repair
  • oxidative stress
  • dna damage response
  • transcription factor
  • type diabetes
  • cell proliferation
  • adipose tissue