miR-346 Inhibited Apoptosis Against Myocardial Ischemia-Reperfusion Injury via Targeting Bax in Rats.

Published in: Drug design, development and therapy (2020)

This study revealed a novel pathway, miR-346/Bax axis, in the regulation of apoptosis in MIRI and which might be a new molecular mechanism and therapeutic target.

Keyphrases

oxidative stress
ischemia reperfusion injury
cell proliferation
endoplasmic reticulum stress
long non coding rna
induced apoptosis
cell cycle arrest
long noncoding rna
cell death
left ventricular
heart failure