Radial linear perivascular emphasis in coronavirus disease 2019-associated acute disseminated encephalomyelitis.
Ryo TanakaTakamasa NukuiRatna Dini HaryuniMakoto MoriShigeru HayashiKyo NoguchiYuji NakatsujiPublished in: Clinical & experimental neuroimmunology (2021)
A 62-year-old woman with coronavirus disease (COVID-19) developed coma on day 19 after her pneumonia was ameliorated. Brain magnetic resonance imaging with gadolinium showed radial linear perivascular enhancement, typically seen in glial fibrillary acidic protein (GFAP) astrocytopathy, although anti-GFAP antibody results were negative. Her consciousness recovered with high-dose steroid administration. We diagnosed the patient with COVID-19-associated acute disseminated encephalomyelopathy (ADEM) with radial linear perivascular emphasis.
Keyphrases
- coronavirus disease
- respiratory failure
- liver failure
- high dose
- magnetic resonance imaging
- respiratory syndrome coronavirus
- ultrasound guided
- aortic dissection
- drug induced
- contrast enhanced
- low dose
- case report
- sars cov
- hepatitis b virus
- extracorporeal membrane oxygenation
- resting state
- ionic liquid
- neuropathic pain
- white matter
- protein protein
- multiple sclerosis
- spinal cord injury
- functional connectivity
- neural network
- cerebral ischemia
- subarachnoid hemorrhage