Vitamin B 12 and a metal-organic framework enable the photocatalytic generation of alkyl radicals.
Krzysztof R DworakowskiArtur ChołujMichał J ChmielewskiDorota GrykoPublished in: Chemical communications (Cambridge, England) (2023)
A versatile Co-catalyst-vitamin B 12 (cobalamin)-can be photochemically reduced to its catalytically active Co(I) form under visible light irradiation, in the presence of MIL-125-NH 2 (Ti) as a photocatalyst and utilized for the generation of alkyl radicals. The prior reduction of cobalamin to the Co(II) form is not required in this method.