Use of intravenous cangrelor in the treatment of ruptured and unruptured cerebral aneurysms: an updated single-center analysis and pooled analysis of current studies.

Pouya EntezamiJohn C DalfinoAlan S BoulosJunichi YamamotoDevin N HoldenNicholas C FieldAndrew K RockEdinson NajeraAlexandra R Paul

Published in: Journal of neurointerventional surgery (2022)

IV cangrelor during aneurysm embolization appears to be safe, with a symptomatic intracranial hemorrhage rate of 4% in ruptured cases and 2.6% in unruptured cases. More research is needed to determine the ideal dosing regimen.

Keyphrases

subarachnoid hemorrhage
abdominal aortic aneurysm
endovascular treatment
middle cerebral artery
internal carotid artery
coronary artery
brain injury
high dose
combination therapy
clinical trial
phase iii