Free Radical Promoted Trifluoromethylthiolation of Alkynes to Access SCF 3 -Containing Dibenzazepines or Dioxodibenzothiazepines.

Persulfate-promoted radical cascade trifluoromethylthiolation of aryl acetylenes with AgSCF 3 provides a simple reaction system for the synthesis of SCF 3 -substituted dibenzazepines or dioxodibenzothiazepines with good Z / E selectivity. The single-crystal X-ray diffraction data confirms the structures of the final products. A series of scaled-up experiments, further transformations, and radical inhibition experiments were operated in the reaction system.