Predicting EGFR mutation status in lung cancer:Proposal for a scoring model using imaging and demographic characteristics.
Ali SabriMadiha BatoolZhaolin XuDrew BethuneMohamed AbdolellDaria ManosPublished in: European radiology (2016)
• EGFR mutation-targeted chemotherapy for bronchogenic carcinoma has a high success rate. • Mutation testing is not possible in all patients. • EGFR associations include subsolid density, slow tumour growth and minimal/no smoking history. • Demographic or imaging features alone are weak predictors of EGFR status. • A scoring system, using imaging and demographic features, is more predictive.