The effect of free and encapsulated cisplatin into long-circulating and pH-sensitive liposomes on IEC-6 cells during wound healing in the presence of host-microbiota.

Raquel Silva Araújo Mônica Cristina Oliveira Valbert Nascimento Cardoso Dorothy M K Keefe Andrea M Stringer

Published in: The Journal of pharmacy and pharmacology (2021)

These results indicate that the presence of microbiota associated with SpHL-CDDP provided less intestinal cellular damages compared with CDDP and constitutes a promising candidate for clinical use.

Keyphrases

wound healing
induced apoptosis
cell cycle arrest
drug delivery
endoplasmic reticulum stress
drug release
signaling pathway
pi k akt