Role of the HIV-1 envelope transmembrane domain in intracellular sorting.

Jackie PerrinAurélie BaryAlexandre VernayPierre Cosson

Published in: BMC cell biology (2018)

These results suggest that the intrinsic properties of the HIV-1 Env transmembrane domain allow the protein to escape ER-retention mechanisms, while maintaining its ability to interact with cellular proteins and to influence cellular physiology.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
reactive oxygen species
small molecule
estrogen receptor
endoplasmic reticulum
protein protein
breast cancer cells