Triple helix and rod structures of the antiseptic drug bibrocathol revealed by electron crystallography.

Erik Svensson Grape Tom Willhammar A Ken Inge

Published in: Chemical communications (Cambridge, England) (2022)

Bibrocathol is an active pharmaceutical ingredient that has been used to treat eyelid diseases for over a century, yet its structure has remained unknown. 3D electron diffraction on crystals from a commercial ointment revealed two structures. These results highlight the technique's potential in structure elucidation from microcrystalline mixtures.

Keyphrases

high resolution
electron microscopy
solar cells
single cell
emergency department
dna binding
electron transfer
human health
mass spectrometry
risk assessment
adverse drug
transcription factor
drug induced