Triple helix and rod structures of the antiseptic drug bibrocathol revealed by electron crystallography.
Erik Svensson GrapeTom WillhammarA Ken IngePublished in: Chemical communications (Cambridge, England) (2022)
Bibrocathol is an active pharmaceutical ingredient that has been used to treat eyelid diseases for over a century, yet its structure has remained unknown. 3D electron diffraction on crystals from a commercial ointment revealed two structures. These results highlight the technique's potential in structure elucidation from microcrystalline mixtures.