Next Generation Sequencing Should Be Proposed to Every Woman With "Idiopathic" Primary Ovarian Insufficiency.

Sarah EskenaziAnne BachelotJustine Hugon-RodinGenevieve Plu-BureauAnne GompelSophie Catteau-JonardDenise Molina-GomesDidier DewaillyCatherine DodéSophie Christin-MaitrePhilippe A Touraine

Published in: Journal of the Endocrine Society (2021)

In our study, a high percentage of patients presented gene variants detected by NGS analysis (38%). Every POI patient should undergo NGS analysis to improve medical cares of the patients.

Keyphrases

end stage renal disease
newly diagnosed
copy number
prognostic factors
peritoneal dialysis
gene expression
patient reported outcomes
dna methylation
genome wide
patient reported
cell free