Indolylkojyl methane analogue IKM5 potentially inhibits invasion of breast cancer cells via attenuation of GRP78.

Debasis NayakArchana KatochDeepak SharmaMir Mohd FaheemSouneek ChakrabortyPromod Kumar SahuNaveed Anjum ChikanHina AminAjai Prakash GuptaSumit G GandhiDebaraj MukherjeeAnindya Goswami

Published in: Breast cancer research and treatment (2019)

Our study warrants IKM5, a potential anticancer agent that can abrogate invasion and metastasis, suggesting its clinical development for the treatment of patients with advanced breast cancer.

Keyphrases

breast cancer cells
cell migration
endoplasmic reticulum stress
combination therapy
risk assessment
replacement therapy