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Empirical carbapenems or piperacillin/tazobactam for infections in intensive care: An international retrospective cohort study.

Nick MeierMarie Warrer MunchAnders GranholmAnders PernerFrederik Boetius HertzBalasubramanian VenkateshNaomi E HammondQiang LiLiesbet De BusJan De WaeleEvaldas KauzonasFredrik SjövallMorten Hylander MøllerMarie Helleberg
Published in: Acta anaesthesiologica Scandinavica (2024)
In this post hoc analysis of ICU patients with infections, we found widespread initial use of carbapenems and piperacillin/tazobactam in international ICUs, with the latter being more frequently used. Randomized clinical trials are needed to assess if the observed variations in outcomes may be drug-related effects or due to confounders.
Keyphrases
  • gram negative
  • intensive care unit
  • mechanical ventilation
  • emergency department
  • type diabetes
  • multidrug resistant
  • adipose tissue
  • acute respiratory distress syndrome
  • weight loss
  • electronic health record