Postmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction.
Thomas MenterJasmin D HaslbauerRonny NienholdSpasenija SavicHelmut HopferNikolaus DeigendeschStephan FrankDaniel TurekNiels WilliHans ParggerStefano BassettiJoerg D LeuppiGieri CathomasMarkus TolnayKirsten D MertzAlexandar TzankovPublished in: Histopathology (2020)
This study provides an overview of postmortem findings in COVID-19 cases, implying that hypertensive, elderly, obese, male individuals with severe cardiovascular comorbidities as well as those with blood group A may have a lower threshold of tolerance for COVID-19. This provides a pathophysiological explanation for higher mortality rates among these patients.
Keyphrases
- sars cov
- coronavirus disease
- end stage renal disease
- oxidative stress
- ejection fraction
- newly diagnosed
- blood pressure
- early onset
- adipose tissue
- metabolic syndrome
- peritoneal dialysis
- prognostic factors
- cardiovascular events
- respiratory syndrome coronavirus
- weight loss
- cardiovascular disease
- low grade
- middle aged
- patient reported outcomes
- coronary artery disease
- bariatric surgery
- high grade