Silver-Polymethylhydrosiloxane-Quaternary Ammonium Coating on Anodized Aluminum with Excellent Antibacterial Property.
Henry AgbeDilip Kumar SarkarX-Grant ChenDavid Dodoo-ArhinPublished in: ACS applied bio materials (2022)
Multidrug-resistant bacteria are known to survive on high-touch surfaces for days, weeks, and months, contributing to the rise in nosocomial infections. Inducing antibacterial property in such surfaces can presumably reduce the overall microbial burden and subsequent nosocomial infections in hygiene critical environments. In the present study, a one-pot sol-gel process has been deployed to incorporate silver (Ag) and quaternary ammonium salt (QUAT) bactericides in a polymethylhydrosiloxane (PMHS) matrix. The Ag-PMHS-QUAT nanocomposite was coated on anodized aluminum (AAO/Al) by a simple ultrasound-assisted deposition process. The morphological features and chemical composition of the Ag-PMHS-QUAT nanocomposite have been characterized using SEM, XRD spectroscopy, and attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR) to confirm the formation of Ag-QUAT nanocomposites within the polymeric network of PMHS. The Ag-PMHS-QUAT nanocomposite coating on anodized aluminum oxide (AAO/Al) coupon exhibited superior antibacterial property with a 6-log bacterial reduction compared to the 5-log reduction for the commercially available antimicrobial copper coupon.
Keyphrases
- quantum dots
- visible light
- highly efficient
- silver nanoparticles
- multidrug resistant
- reduced graphene oxide
- gold nanoparticles
- acinetobacter baumannii
- carbon nanotubes
- oxide nanoparticles
- wound healing
- drug delivery
- staphylococcus aureus
- klebsiella pneumoniae
- ionic liquid
- drug resistant
- anti inflammatory
- gram negative
- methicillin resistant staphylococcus aureus
- oxidative stress
- hyaluronic acid
- mass spectrometry
- risk factors
- liquid chromatography
- network analysis