Combining adverse pregnancy and perinatal outcomes for women exposed to antiepileptic drugs during pregnancy, using a latent trait model.

Xuerong WenAbraham HartzemaJoseph A DelaneyBabette BrumbackXuefeng LiuRobert EgermanJeffrey RothRich SegalKimford J Meador

Published in: BMC pregnancy and childbirth (2017)

Latent trait modeling can be an effective tool for combining adverse pregnancy and perinatal outcomes to assess prenatal exposure to AED, but evaluation of the selected components is essential to ensure the validity of the combined outcome.

Keyphrases

pregnancy outcomes
pregnant women
preterm birth
genome wide
polycystic ovary syndrome
type diabetes
gene expression
adipose tissue
metabolic syndrome
weight loss
electronic health record
drug induced