Incidence and risk factors of antituberculosis drug-induced liver injury in India: A systematic review and meta-analysis.

Ramesh KumarAbhishek KumarRishabh Patel Sabbu Surya Prakash Sudhir KumarHimanshu SuryaSudheer Marrapu

Published in: Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology (2024)

Overall, 12.6% patients of tuberculosis in India developed ATDILI when combination of first-line antituberculosis drugs was used. An average of 7% of ATDILI patients progressed to ALF which had a high mortality rate. Older age, female, poor nutritional status and some genetic polymorphisms were identified as significant risk factors.

Keyphrases

end stage renal disease
risk factors
ejection fraction
chronic kidney disease
newly diagnosed
emergency department
type diabetes
cardiovascular disease
patient reported outcomes
cardiovascular events
coronary artery disease
hiv aids
adverse drug
electronic health record