Eosinophil-derived neurotoxin levels in early childhood and association with preschool asthma - A prospective observational study.
Martin FärdigAnine LieMagnus P BorresTina EkenkrantzBerit GranumGuttorm HaugenChristine M JonassenRobert MovérareEva Maria RehbinderHåvard O SkjervenAnne CathrineRiyas VettukattilKarin C Lødrup CarlsenCilla SöderhällBjörn NordlundPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2023)
We report EDN values in early childhood, demonstrating higher levels at 1 compared to 3 years and in boys compared to girls at both ages. Higher EDN levels at both ages were associated with preschool asthma. However, EDN cut-off levels for preschool asthma were overall lower than the ULN of non-atopic children, limiting translation into clinical practice.