Synergistic regenerative therapy of thin endometrium by human placenta-derived mesenchymal stem cells encapsulated within hyaluronic acid hydrogels.

Yifeng LinShunni DongXiaohang YeJuan LiuJiaqun LiYanye ZhangMixue TuSiwen WangYanyun YingRuixue ChenFeixia WangFeida NiJianpeng ChenBinyang DuDan Zhang

Published in: Stem cell research & therapy (2022)

Our study suggested the potential therapeutic effects and the underlying mechanisms of HP-MSCs-HA on treating thin endometrium. HA hydrogel could be a preferable delivery method for HP-MSCs, and the strategy represents a promising therapeutic approach against endometrial injury in clinical settings.

Keyphrases

hyaluronic acid
mesenchymal stem cells
umbilical cord
endothelial cells
stem cells
tissue engineering
drug delivery
cell therapy
induced pluripotent stem cells