Integrative Analysis of m6A RNA Methylation Regulators and the Tumor Immune Microenvironment in Non-Small-Cell Lung Cancer.

Jiaqi ZhuYun JiangTianyi WangAnqi WuTingting ZhouAnping ZhangYijie TangZihao ShenJinjie WangHao ZhouJia-Hai Shi Jianle Chen

Published in: Disease markers (2022)

The results suggest that m6A RNA methylation regulators make an important difference in the tumor immune microenvironment of patients with NSCLC. m6A gene characterization and the construction of the m6Ascore provide us with a richer understanding of m6A RNA methylation modification patterns in NSCLC patients and help to predict clinical prognosis and immunotherapeutic response.

Keyphrases

genome wide
small cell lung cancer
dna methylation
stem cells
end stage renal disease
newly diagnosed
ejection fraction
transcription factor
chronic kidney disease
advanced non small cell lung cancer
nucleic acid
prognostic factors
copy number
patient reported outcomes
patient reported
tyrosine kinase