Predictors of bone mineral density in patients receiving glucocorticoid replacement for Addison's disease.

Katarzyna FurmanPaweł GutAnna SowińskaMarek RuchałaMarta Fichna

Published in: Endocrine (2024)

Standard HC substitution does not considerably accelerate BMD loss in AD patients and their serum BTMs: CTX, osteocalcin, sclerostin, DKK-1, and ALP activity remain within the reference ranges. Independent predictors of low lumbar spine BMD, especially ALP activity, serum CTX and sclerostin, might be monitored during GC substitution.

Keyphrases

bone mineral density
postmenopausal women
end stage renal disease
body composition
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
klebsiella pneumoniae
escherichia coli
patient reported outcomes
mass spectrometry