Balanced crystalloid solutions versus normal saline in intensive care units: a systematic review and meta-analysis.
Puze WangYin HuangJin LiDehong CaoBo ChenZeyu ChenJinze LiRuyi WangLiang-Ren LiuPublished in: International urology and nephrology (2023)
Compared with saline, balanced crystalloid solutions could not reduce the risk of mortality and renal-related outcomes, including MAKE30, RRT, maximum creatinine increasing, maximum creatinine level, and final creatinine level ≥ 200% of baseline, but the solutions may reduce total AKI incidence among adult patients in ICUs. For service utilization outcomes, balanced crystalloid solutions were associated with a longer length of ICU stay in the adult group and shorter length of hospital stay in the pediatric group.
Keyphrases
- intensive care unit
- uric acid
- healthcare
- risk factors
- acute kidney injury
- mental health
- mechanical ventilation
- cardiovascular events
- type diabetes
- emergency department
- cardiovascular disease
- young adults
- acute respiratory distress syndrome
- acute care
- childhood cancer
- metabolic syndrome
- weight loss
- glycemic control
- adverse drug