A Tale of Two Histologies: Dissecting the Biology of Lineage Transformation in Lung Cancer.

Published in: Cancer discovery (2022)

Lineage plasticity is an important, and likely underappreciated, mechanism of treatment resistance in lung cancer. Here, Quintanal-Villalonga and colleagues integrate results from multiomic analyses to provide key new insights into the biology of lineage plasticity. See related article by Quintanal-Villalonga et al., p. 3028.

Keyphrases

single cell
cell fate
combination therapy