In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli.
Fabien Le ChevalierIsabelle CorreiaLucrèce MatheronMorgan BabinMireille MoutiezNicolas CanuMuriel GondryOlivier LequinPascal BelinPublished in: Microbial cell factories (2020)
Our study establishes the usefulness of CDPS and CDO for the bioproduction of dehydrogenated cyclodipeptides. It constitutes the first step toward the bioproduction of more complex and diverse 2,5-diketopiperazines.
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