Monoaminergic degeneration, cognition, and autonomic symptom trajectory in early Parkinson's disease.

Seoyeon KimKyung Ah WooHongyoon ChoiJung Hwan ShinHan-Joon Kim

Published in: Parkinsonism & related disorders (2024)

Brainstem non-dopaminergic dysfunction in early PD is linked to cognitive dysfunction and predicts progression in gastrointestinal symptoms, offering potential indicators for worsening non-motor trajectories.

Keyphrases

oxidative stress
depressive symptoms
heart rate
mild cognitive impairment
blood pressure
sleep quality
climate change
risk assessment
patient reported