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Genomic selection models for directional dominance: an example for litter size in pigs.

Luis VaronaAndrés LegarraWilliam HerringZulma G Vitezica
Published in: Genetics, selection, evolution : GSE (2018)
Our results confirmed the presence of positive directional dominance for pig litter size and suggested that it should be taken into account when dominance effects are included in genomic evaluation procedures. The consequences of ignoring directional dominance may affect predictions of breeding values and can lead to biased prediction of inbreeding depression and performance of potential mates. A model that assumes Gaussian dominance effects that are centered on a non-zero mean is recommended, at least for datasets with similar features to those analyzed here.
Keyphrases
  • copy number
  • rna seq
  • dna methylation
  • single cell