In vitro modulatory effect of dehydroepiandrosterone sulfate on apoptosis and expression of apoptosis-related genes in patients with systemic lupus erythematosus.

Bahman YousefiMaryam RastinMohammad Reza HatefJaleh ShariatiReza AlimohammadiMahmoud Mahmoudi

Published in: Journal of cellular physiology (2018)

DHEAS reduced the apoptosis rate in PBLs from SLE patients and may decrease the load of autoantigens. Therefore, DHEAS might be considered as a therapeutic tool in SLE patients.

Keyphrases

end stage renal disease
oxidative stress
newly diagnosed
ejection fraction
systemic lupus erythematosus
chronic kidney disease
cell death
prognostic factors
patient reported outcomes