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Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma.

Marta E CapalaKatrin S PachlerIris LauwersMaarten A de KorteNicole S VerkaikHetty MastBrend P JonkerAniel SewnaikJose Angelito U HardilloStijn KeereweerDominiek A MonserezSenada KoljenovicBianca MostertGerda M VerduijnSteven PetitDik C van Gent
Published in: Cancers (2023)
Our functional ex vivo assay discriminated between IR-sensitive and IR-resistant HNSCC tumors, and may also be suitable for predicting response to cisplatin. Its predictive value is currently under investigation in a prospective clinical study.
Keyphrases
  • high throughput