Kukoamine B Ameliorate Insulin Resistance, Oxidative Stress, Inflammation and Other Metabolic Abnormalities in High-Fat/High-Fructose-Fed Rats.

Quan ZhaoLinhai LiYu ZhuDezhi HouYuejin LiXiaodong GuoYongzhi WangOpeyemi Joshua OlatunjiPing WanKunmei Gong

Published in: Diabetes, metabolic syndrome and obesity : targets and therapy (2020)

These results indicated that Kuk B showed protective effect against HFDFr-induced metabolic disorders by downregulating lipid accumulation, oxidative stress and inflammatory factors.

Keyphrases

oxidative stress
diabetic rats
insulin resistance
dna damage
ischemia reperfusion injury
induced apoptosis
adipose tissue
metabolic syndrome
type diabetes
high glucose
high fat diet
skeletal muscle
polycystic ovary syndrome
heat shock
endoplasmic reticulum stress
heat shock protein