Tenebrio molitor as an Alternative Model to Analyze the Sporothrix Species Virulence.
Nancy E Lozoya-PérezLaura C García-CarneroJosé Ascención Martínez-ÁlvarezIván Martínez-DunckerHéctor Manuel Mora-MontesPublished in: Infection and drug resistance (2021)
The study demonstrated that T. molitor larvae are an appropriate alternative invertebrate model to analyze the virulence of S. schenckii, S. brasiliensis, and S. globosa. Additionally, hemocyte levels, phenoloxidase activity, cytotoxicity, uptake by hemocytes, and immunological priming are biological parameters that can be used to study the Sporothrix-T. molitor interaction.