Telomerase activity, telomere length, and the euploidy rate of human embryos.

Maria LongoErmanno GrecoIlaria ListortiMaria Teresa VarricchioKaterina LitwickaCristiana ArriviCecilia MencacciPier Francesco Greco

Published in: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology (2024)

LTL shows a significant inverse correlation with patient age and higher aneuploidy rates. Telomere length in GCs does not correlate with patient age or reproductive outcomes, indicating differential telomere dynamics between leukocytes and granulosa cells.

Keyphrases

case report
induced apoptosis
endothelial cells
cell cycle arrest
type diabetes
peripheral blood
polycystic ovary syndrome
metabolic syndrome
induced pluripotent stem cells
cell death
skeletal muscle