The risk of skin cancer in women who carry BRCA1 or BRCA2 mutations.
Steven A NarodKelly MetcalfeAmy FinchAn-Wen ChanSusan Randall ArmelAmber AeiltsAndrea EisenBeth KarlanLouise BordeleauNadine TungWilliam D FoulkesSusan L NeuhausenCharis EngOlufunmilayo OlopadeDana ZakalikFergus CouchCarey CullinaneTuya PalPing SunJoanne Kotsopoulosnull nullPublished in: Hereditary cancer in clinical practice (2024)
The risk of non-melanoma skin cancer in women who carry a mutation in BRCA1 or BRCA2 is similar to that of non-carrier women. The risk of melanoma appears to be slightly elevated. We suggest that a referral to a dermatologist or primary care provider for BRCA mutation carriers for annual skin examination and counselling regarding limiting UV exposure, the use of sunscreen and recognizing the early signs of melanoma might be warranted, but further studies are necessary.