Syncytin 1, CD9, and CD47 regulating cell fusion to form PGCCs associated with cAMP/PKA and JNK signaling pathway.

Fei FeiChunyuan LiXinlu WangJiaxing DuKai LiuBo LiPeiyu YaoYuwei LiShiwu Zhang

Published in: Cancer medicine (2019)

These data indicate that the cell fusion-related proteins syncytin 1, CD9, and CD47 may be involved in PGCC formation, and that cAMP/PKA and JNK signaling is likely to promote PGCC formation via the regulation of cell fusion processes.

Keyphrases

signaling pathway
single cell
cell therapy
cell death
nk cells
induced apoptosis
epithelial mesenchymal transition
pi k akt
big data