Bi-directional modulation of cellular interactions in an in vitro co-culture model of tendon-to-bone interface.

Isabel Calejo Raquel Costa-Almeida Ana Isabel Gonçalves Dominika Berdecka Rui Luis Reis Manuela Estima Gomes

Published in: Cell proliferation (2018)

The present work assessed both the influence of OM on cell phenotype modulation and the importance of co-culture models while promoting cell-cell interactions and the exchange of soluble factors in triggering an interface-like phenotype to potentially modulate enthesis regeneration.

Keyphrases

single cell
cell therapy
stem cells
bone mineral density
bone marrow
soft tissue