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Genetic variation of Mycoplasma hyopneumoniae from Brazilian field samples.

Viviane Sisdelli AssaoThalita Moreira ScatamburloElaine Nery AraujoMarcus Rebouças SantosCarlos Eduardo Real PereiraRoberto Maurício Carvalho GuedesGustavo Costa BressanJuliana Lopes Rangel FiettoYung-Fu ChangMaria Aparecida Scatamburlo MoreiraAbelardo Silva-Júnior
Published in: BMC microbiology (2019)
This work demonstrated the genetic diversity of several Mhp field strains based on 16 selected genes related to virulence and/or immune response in Brazil. Our findings demonstrate the difference between Mhp field strains could influence the virulence, and we hypothesize that the most frequent genes in Mhp field strains could possibly be used as vaccine candidates. Based on our results, we suspect that Mhp genetic variability may be associated with the frequency of genes among the field strains and we have demonstrated that some Mhp field samples could not have many important genes described in the literature.
Keyphrases
  • escherichia coli
  • genome wide
  • immune response
  • genetic diversity
  • pseudomonas aeruginosa
  • bioinformatics analysis
  • staphylococcus aureus
  • biofilm formation
  • gene expression
  • copy number
  • inflammatory response