IgG from atopic dermatitis patients induces non-atopic infant thymic invariant natural killer T (iNKT) cells to produce IL-4, IL-17, and IL-10.
Ludimila S SantosFabio da Ressureição SgnottoThamires R SousaRaquel L OrfaliValéria AokiAlberto José da Silva DuarteJefferson Russo VictorPublished in: International journal of dermatology (2019)
These observations suggest that IgG from AD patients can induce a cytokine profile by thymic iNKT cells from non-atopic infants compatible with the observations in AD development, which can collaborate with the elucidation of AD pathogenesis.