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Biopsy for molecular risk stratification in uveal melanoma: Yields and molecular characteristics in 119 patients.

Vivian LinIn Young ChungElsa ToumiDaniel McKayJohn McKenziePenny McKelvieFarida ZabihAlexandra HoffmeisterDale WrightAphrodite NtzaferiIris Junhong WuLuke HessonAdrian FungLi-Anne S LimStephen WongAndrew FieldPeter EarlsMichael GiblinRobert Max ConwaySvetlana Cherepanoff
Published in: Clinical & experimental ophthalmology (2021)
All three biopsy instruments provide similar cytological yields as post-enucleation sampling, although post-enucleation samples had a more successful chromosome microarray yield. Epithelioid cytomorphology alone is insufficient for prognostication in in vivo biopsies, immunohistochemistry would be a useful surrogate test.
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