Reliable blood cancer cells' telomere length evaluation by qPCR.

Joana RopioAlain CheblyJacky FerrerMartina Prochazkova-CarlottiYamina IdrissiLamia Azzi-MartinDavid CappellenAnne Pham-LedardPaula SoaresJean-Philippe MerlioEdith Chevret

Published in: Cancer medicine (2020)

Our study provides guidance and recommendations for accurate telomere length measurement by qPCR in cancer cells, taking advantage of our expertise in telomere homeostasis investigation in primary cutaneous T-cell lymphomas. Furthermore, our data emphasize the requirement of samples with both, high DNA quality and high tumor cells representation.

Keyphrases

electronic health record
high resolution
single molecule
big data
mass spectrometry