Added value of semiquantitative analysis of brain FDG-PET for the differentiation between MCI-Lewy bodies and MCI due to Alzheimer's disease.

Federico MassaAndrea ChincariniMatteo BaucknehtStefano RaffaEnrico PeiraDario ArnaldiMatteo PardiniMarco PaganiBeatrice OrsoMaria Isabella DoneganiAndrea BrugnoloErica BiassoniPietro MattioliNicola GirtlerUgo Paolo GuerraSilvia MorbelliFlavio Nobili

Published in: European journal of nuclear medicine and molecular imaging (2021)

Conventional visual reading of FDG-PET is moderately accurate in distinguishing between MCI-LB and MCI-AD, and is not significantly improved by univariate single-subject VBA but by a VROI analysis built on macro-regions, allowing for high accuracy independent of reader skills.

Keyphrases

mild cognitive impairment
pet ct
positron emission tomography
pet imaging
cognitive decline
computed tomography
parkinson disease
high resolution
resting state
mass spectrometry
blood brain barrier