Ciliary dyskinesia in severe asthma is not affected by chronic mucus hypersecretion.

Céline Kempeneers Romane BonhiverNoëmie BricmontMaud PirotteSara EngelskirchenLionel BenchimolDoriane CalmesFrançoise GuissardCatherine Moermans Marie-Christine SeghayeRenaud LouisFlorence Schleich

Published in: ERJ open research (2023)

Chronic mucus hypersecretion (CMH) is linked to increased asthma severity. Ciliary dyskinesia is present in severe asthma but CMH was not associated with a worse ciliary dysfunction, suggesting another mechanism to explain chronic cough and phlegm. https://bit.ly/3JNUgGr.

Keyphrases

chronic obstructive pulmonary disease
oxidative stress
lung function
drug induced