Oncologic effects of preoperative biliary drainage in resectable hilar cholangiocarcinoma: Percutaneous biliary drainage has no adverse effects on survival.
Xu-Feng ZhangEliza Wright BealKatiuscha MerathCecilia G EthunAhmed SalemSharon M WeberThuy TranGeorge PoultsidesAndre Y SonIoannis HatzarasLinda JinRyan C FieldsMatthew WeissCharles ScogginsRobert C G MartinChelsea A IsomKamron IdreesHarveshp D MogalPerry ShenShishir K MaithelCarl R SchmidtTimothy M PawlikPublished in: Journal of surgical oncology (2017)
The median decrease in total bilirubin levels after biliary drainage was similar comparing PTBD (n = 104) versus EBD (n = 92) (mg/dL, 4.9 vs 4.9, P = 0.589) before surgery. There was no difference in baseline demographic characteristics, type of surgical procedure performed, final AJCC tumor stage or postoperative morbidity among patients who underwent EBD only versus PTBD (all P > 0.05). Patients who underwent PTBD versus EBD had a comparable long-term DSS (median, 43.7 vs 36.9 months, P = 0.802) and RFS (median, 26.7 vs 24.0 months, P = 0.571). The overall pattern of recurrence relative to regional or distant disease was also the same among patients undergoing PTBD and EBD (P = 0.669) CONCLUSIONS: Oncologic outcomes including DSS and RFS were similar among patients who underwent PTBD versus EBD with no difference in tumor recurrence location.
Keyphrases
- patients undergoing
- minimally invasive
- ultrasound guided
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- rectal cancer
- emergency department
- ejection fraction
- peritoneal dialysis
- prognostic factors
- metabolic syndrome
- robot assisted
- atrial fibrillation
- radical prostatectomy
- insulin resistance
- adverse drug