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Just add water? Chlorhexidine's antimicrobial properties are minimally affected by dilution in saline compared to water.

David Rojas VintimillaLori ChambersCyril MauffreyJoshua Alan Parry
Published in: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie (2019)
Dilute CHG in normal saline, versus sterile water, retained its antimicrobial activity with a small reduction in the zone of inhibition. Surgeons and scientists should be aware of the interaction between normal saline and CHG. Future scientific studies need to control for what solution is used for dilution.
Keyphrases
  • liquid chromatography tandem mass spectrometry
  • staphylococcus aureus
  • liquid chromatography
  • gas chromatography
  • mass spectrometry
  • high resolution