Association between markers of immune response at hospital admission and COVID-19 disease severity and mortality: A meta-analysis and meta-regression.
Jaskaran KhindaNaveed Zafar JanjuaShannon ChengEdwin R van den HeuvelParveen BhattiMaryam DarvishianPublished in: Journal of medical virology (2020)
The results highlight that hyper inflammation, blunted adaptive immune response, and intravascular coagulation play key roles in the pathogenesis of COVID-19. Markers of these processes are good candidates to identify patients for early intervention and, importantly, are likely reliable regardless of age or sex in adult patients.
Keyphrases
- immune response
- coronavirus disease
- sars cov
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- oxidative stress
- healthcare
- dendritic cells
- peritoneal dialysis
- coronary artery
- toll like receptor
- prognostic factors
- type diabetes
- risk factors
- coronary artery disease
- patient reported outcomes
- respiratory syndrome coronavirus
- acute care
- electronic health record
- drug induced