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Garlic Extract Promotes Pancreatic Islet Neogenesis Through α-to-β-Cell Transdifferentiation and Normalizes Glucose Homeostasis in Diabetic Rats.

Amani M Al-AdsaniKhaled K Al-QattanSahar A BarhoushManal S AbboodSuzanne A Al-Bustan
Published in: Molecular nutrition & food research (2024)
GE induces β-cell neogenesis in DRs and restores islet architecture. The newly formed mature β-like cells could have originated through the differentiation of endocrine progenitor cells as well as α- to β-cell transdifferentiation.
Keyphrases
  • single cell
  • cell therapy
  • diabetic rats
  • oxidative stress
  • stem cells
  • adipose tissue
  • insulin resistance