The severe epilepsy syndromes of infancy: A population-based study.
Katherine B HowellJeremy L FreemanMark T MackayMichael C FaheyJohn ArcherSamuel Frank BerkovicEunice ChanGabriel DabscheckStefanie EggersMichael HaymanJames HolbertonRodney W HuntSusan E JacobsAndrew J KornbergRichard J LeventerSimone MandelstamJacinta M McMahonHeather C MeffordJulie PanettaJessica RiseleyVictoria Rodriguez-CaseroMonique M RyanAmy L SchneiderLindsay J SmithZornitza StarkFlora WongEppie M YiuIngrid E SchefferA Simon HarveyPublished in: Epilepsia (2021)
Three quarters of severe epilepsies of infancy could be assigned an epilepsy syndrome or "variant syndrome" at presentation. In this era of genomic testing and advanced brain imaging, diagnosing epilepsy syndromes at presentation remains clinically useful for guiding etiologic investigation, initial treatment, and prognostication.