Hepatotoxicity Induced by Azole Antifungal Agents: A Review Study.

Amin RakhshanBardia Rahmati KamelAli Saffaei Maria Tavakoli Ardakani

Published in: Iranian journal of pharmaceutical research : IJPR (2023)

Clinical evaluations regarding the hepatotoxicity of antifungal agents provided in the literature were reviewed. Therefore, it is recommended to prescribe these drugs with caution in high-risk patients suffering from liver diseases, and patients should be monitored for hepatotoxicity. However, more research is needed to evaluate the hepatotoxicity of azole antifungal agents and select appropriate drugs according to cost-effectiveness and the side effects' profiles, relying on lower incidence of this liver complication.

Keyphrases

candida albicans
end stage renal disease
drug induced
chronic kidney disease
ejection fraction
newly diagnosed
prognostic factors
risk factors
patient reported