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Latent Tuberculosis Infection Screening and Treatment in Congregate Settings (TB FREE COREA): Demographic Profiles of Interferon-Gamma Release Assay Cohort.

Hyung Woo KimJinsoo MinJoon Young ChoiAh Young ShinJun-Pyo MyongYun-Hee LeeHyeon-Woo YimHyeon Woo YimSanghyuk BaeEunhye ShimHyekyung InChaemin ChunGahee KimJi Young KangSung Soon LeeJae Seuk ParkJu Sang Kim
Published in: Journal of Korean medical science (2021)
In 2017, the Korean government launched an unprecedentedly large-scaled latent tuberculosis infection (LTBI) screening project which covered more than a million individuals in congregate settings. A total of 1,047,689 participants of source population (n = 2,336,157) underwent LTBI testing from 2017 to 2018. The overall LTBI test uptake rate during this project was 44.8%. Workers in daycare centers (83.5%) and kindergartens (78.9%) showed high participation rate. A total of 1,012,206 individuals with valid results of interferon-gamma release assay (IGRA) were selected to constitute the IGRA cohort. Most of the enrolled participants in the IGRA cohort were in their working age. Approximately, three-quarters of total enrolled population were female. Investigating the LTBI prevalence, stages of LTBI care cascade, natural history of LTBI, efficacy of LTBI treatment and cost-effectiveness of LTBI screening are feasible within this IGRA cohort.
Keyphrases
  • mycobacterium tuberculosis
  • quality improvement
  • healthcare
  • high throughput
  • emergency department
  • immune response
  • hepatitis c virus