A Case Series of Patients with Isolated IgG4-related Hypophysitis Treated with Rituximab.
Hessa BoharoonJames TomlinsonClara Limback-StanicAnastasia GontsorovaNiamh MartinEmma HatfieldKarim MeeranRamesh NairNigel MendozaJeremy LevySteve McAdooCharles PuseyFlorian WernigPublished in: Journal of the Endocrine Society (2020)
Rituximab treatment for IgG4-related hypophysitis resulted in sustained remission in 2 patients treated early in the disease process but only achieved partial response in a patient with chronic disease, suggesting that early therapeutic intervention may be crucial in order to avoid irreversible changes.