Serum proprotein convertase subtilisin/Kexin type 9 and vascular disease in type 2 diabetic patients.
Giuseppe ArmentaroFederico CarboneVelia CassanoLuca LiberaleSilvia MinettiMaria Bianca BertolottoGaia ManninoTeresa V FiorentinoMaria PerticoneElena SuccurroGiorgio SestiFabrizio MontecuccoFrancesco AndreozziAngela SciacquaPublished in: European journal of clinical investigation (2022)
Our study demonstrates a close association between circulating PCSK9 levels and PWV in T2DM subjects without previous CV events even after adjusting for well-known CV risk factor and pharmacological medications. Serum PCSK9 could be a useful biomarker for CV risk stratification in diabetic subjects.